![]() ![]() The relationship between the induction of paresthesia and analgesia was therefore assumed to be linked given that the location of pain relief has been demonstrated to correlate with paresthesia overlap. Historically, antidromic activation of the nerve fibers in the dorsal columns has been thought by some to be capable of ‘closing the gate’ resulting in analgesia, while orthodromic activation elicits paresthesias. Paresthesia-based spinal cord stimulation (SCS) has been used for decades to treat chronic pain. This rapid analgesic onset achieved with the novel FAST technique suggests the potential for an alternative mechanism of action(s) of sub-perception SCS. At last follow up (mean = 223 ± 132 days), a pain score of 1.6 ± 0.3, n = 30 was determined.Ĭonclusions: After FAST implementation, a profound analgesic response, requiring substantially less energy than conventional sub-perception methodologies, was observed. ![]() Results: Mean overall pain score at baseline was 8.4 ± 0.2 (n = 41). Pain scores (NRS) were collected as reported per standard-of-care from patient charts. Methods: This observational case-series evaluated patients implanted with an SCS device for chronic pain, who underwent re-programming utilizing a new methodology in which paresthesia was used to guide sub-perception stimulation field targeting at specific parameters including charge-balanced symmetrical pulses at 90 Hz (termed Fast-Acting Sub-Perception Therapy, FAST). We describe the attainment of clinically meaningful and rapid-onset analgesic outcomes using a novel sub-perception SCS approach. ![]() duration until maximum pain relief) and prolonged assessment of therapy. Background: Treating chronic pain using sub-perception Spinal Cord Stimulation (SCS) does not elicit paresthesia but is associated with long analgesic ‘wash-in’ (i.e. ![]()
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